Biosafety Cabinet Level 1

Biosafety level 1 overview.

Biosafety cabinet level 1.

Level 1 biosafety level one the lowest level applies to work with agents that usually pose a minimal potential threat to laboratory workers and the environment and do not consistently cause disease in healthy adults. Purifier cell logic type a2 and b2 biosafety cabinets have features specialized for cell research. A biosafety cabinet bsc also called a biological safety cabinet or microbiological safety cabinet is an enclosed ventilated laboratory workspace for safely working with materials contaminated with or potentially contaminated with pathogens requiring a defined biosafety level several different types of bsc exist differentiated by the degree of biocontainment required. Like class i cabinets class ii cabinets are safe for work using agents requiring biosafety level 1 2 or 3 containment.

Class ii bscs the most common cabinets used in laboratories are designed to provide personnel protection for you and those around you product protection for your samples and environmental protection. They may exhaust hepa filtered air back into the lab or may be exhaust outside using a canopy connection. The laboratory is not necessarily separated from the general traffic patterns in the building. Biosafety level 1 practices safety equipment and facilities appropriate for work with defined and characterized strains of viable micro organisms not known to cause disease in healthy adult humans.

Special containment practices and devices are generally not required but institutional laboratory practices must be implemented to reduce risk to laboratory personnel. Biosafety level 1 is specified as work with well characterized agents that are known not to cause disease in healthy non immunocompromised adults. Bsl 1 as the lowest of the four biosafety level 1 applies to laboratory settings in which personnel work with low risk microbes that pose little to no threat of infection in healthy adults. Purifier logic class ii type a2 and type b2 biological safety cabinets provide personnel product and environmental protection from hazardous particulates and agents that require biosafety level 1 2 or 3 containment.

Basic laboratory design for biosafety levels 1 and 2 containment facilities are described in the cdc nih publication biosafety in microbiological and biomedical laboratories bmbl and in the nih guidelines for research involving recombinant or synthetic nucleic acid molecules nih guidelines. An example of a microbe that is typically worked with at a bsl 1 is a nonpathogenic strain of e. Bsl 1 laboratory facilities 1. Type a1 a class ii type a1 cabinet must maintain a minimum average inflow velocity of 75 fpm through the sash opening.